Pepsin (English name: Pepsin) is a kind of peptic action, by the gastric mucosa of main cells in the stomach (gastric devoted to cell) secretion, function is the protein in the food into small peptide fragments.Primary cells secrete pepsinogen, pepsin, after gastric acid and pepsin to stimulate the formation of pepsin, pepsin is not generated directly by the cell.

clinical significance：Pepsin main reason stomach bottom cell secretion, under the condition of pH1.5 ~ 5.0, activated pepsin, decompose the protein peptone, and part is broken into tyrosine, phenylalanine and other amino acids.Gastric pepsin determination can be used to identify neuropathic disease, low acid disease and stomach acid when too little stomach acid or the lack of pepsin content sometimes normal compared to hydrochloric acid and pepsin lack at the same time.Generally considered sex low acid stomach disease is caused due to severe organic gastric mucosal changes, especially for pernicious anemia, acid, pepsin secretion is seen as important diagnostic. Chronic gastritis, chronic stomach expansion twelve fat, chronic enteritis and pepsin secretion is often reduced.

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