Scutellaria baicalensis was among seven ingredients in a combination oral herbal product known as PC-SPES that was used to treat prostate cancer. The U.S. Food and Drug Administration (FDA) initiated a nationwide recall of all PC-SPES in 2002 because the capsules were found to contain varying amounts of prescription drugs.

Other combination formulas containing Scutellaria baicalensis are used in Asian medicine to improve impaired brain function and to treat headaches.

Skullcap is an herbaceous perennial mint with ridged leaves and tiny flowers that can range in color from purple and blue to pink and white. The two-lobed flowers resemble the military helmets worn by early European settlers, hence the herb’s name. A hardy plant, it grows 1 to 4 feet (25 cm to 1 m) high, thriving in the woods and swamplands of eastern North America. Settlers in the late 1700’s promoted the herb’s effectiveness as a cure for rabies, giving rise to one of its common names, mad dog weed. This claim was later discarded, and herbalists began to focus on the plant’s considerable value.

Application

1,Baikal skullcap is used to treat respiratory infections, hay fever, and fever. It is also used for gastrointestinal (GI) infections, as well as livers problems including viral hepatitis and jaundice.

2,Baikal skullcap for HIV/AIDS, kidney infections, pelvic inflammation, and sores or swelling. It is also used for ,scalet fever,headache , irritability, red eyes , flushed face, seizures, , hysteria, nervous tension, and to relieve a bitter taste in the mouth.

3,The active ingredient in Baikal skullcap, baicalin, is used in combination with shung hua (ephedra) to treat upper respiratory tract infections. In combination with other herbs, Baikal skullcap is used to treat attention-deficit hyperactivity disorder (ADHD),prostate cancer , a lung condition called bronchiolitis, arthritis and hemorrhoids.

4,Baikal skullcap is also sometimes applied to the skin for psorasis.

Medicinal Uses and Indications

 While scientific studies have not been conducted on the medicinal properties of Scutellaria lateriflora, its current uses, based on traditional and clinical practice, include:

 Treatment of muscle spasms

Calming of the nerves

It has also been used to treat symptoms associated with:

Tension headache

Anorexia nervosa

Anxiety

Fibromyalgia

Restless leg syndrome and other causes of insomnia

Mild Tourette's syndrome (a disorder characterized by multiple motor and vocal tics)

Seizure disorders.

Chinese Skullcap

A closely related herb, Chinese skullcap (Scuterllaria baicalensis) has actually been the subject of a number of studies, including those on animals and people. It has anti-oxidative, anti-inflammatory, and antihistamine properties, which can help treat allergies such as hay fever (called allergic rhinitis), particularly when used with other herbs, including stinging nettle. 

Cancer

Chinese skullcap is also used in Traditional Chinese Medicine to treat tumors. Early laboratory studies investigating this traditional use are emerging and showing preliminary promise for combating bladder, liver, and other types of cancers, at least in test tubes.

 In terms of clinical studies on people, skullcap is also one of the eight herbs that make up PC-SPES, an alternative treatment for prostate cancer. (It is important to note, however, that the U.S. Food and Drug Administration [FDA] recently issued a warning to consumers that PC SPES may contain undeclared prescription drug ingredients that could cause dangerous side effects.)

 Other

Chinese laboratory research has isolated an element present in skullcap that may prove useful in treating hepatitis B and has suggested that the antioxidant properties of Chinese skullcap may prove beneficial for preventing heart disease or limiting the damage following a heart attack. Much more research needs to be done in these areas before conclusions can be drawn.

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