Taxus Brevifolia Extract 

About Paclitaxel:

Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a US National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it taxol. Later it was discovered that endophytic fungi in the bark synthesize paclitaxel.Paclitaxel is used to treat patients with lung, ovarian, breast, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is also used for the prevention of restenosis.

Paclitaxel stabilizes microtubules and as a result, interferes with the normal breakdown of microtubules during cell division. Together with docetaxel, it forms the drug category of the taxanes. It was the subject of a notable total synthesis by Robert A. Holton.

Health Benefits:

1, Paclitaxel is mainly applied to ovarian and breast cancer, lung cancer, colorectal cancer,melanoma, head and neck cancer, lymphoma. Also have a certain effect on brain tumors.

2, This product is stability drugs that can promote microtubule polymerization and microtubule polymerization

3, There will be accumulated a large number of microtubules in the cells after exposure to paclitaxel, the accumulation of microtubules interferes with cell functions, in particular, stoped cell division in mitosis, blocking normal cell division.

Application:

Pharmaceutical stuff;

Functional food and food additive;

Cosmetics additive;

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