Rhizoma Curculiginis Extract 

• Name: Rhizoma Curculiginis Extract
• INCI Name: Curculigo Orchioides / Xian Mao
• Plant Part Used : Root
• Specifications: 4:1, 5:1, 10:1
• Appearance: Brownish Powder
• Extract Method: Water
• Active Ingredient: Curculigoside Curculigoside
• Mol.Formula: C22H26O11
• Mol.Weight: 466.4352
• CAS #: 85643-19-2

Health Benefits

1. Antibacteria lactivity

The alpha-citral (geranial) and beta-citral (neral) components of Cymbopogon citratus (DC.) Stapf., a medical plant used over many years in West Africa individually elicit antibacterial action on gram-negative and gram-positive organisms, the third component, myrcene, did not show observable antibacterial activity on its own. However, myrcene provided enhanced activities when mixed with either of the other two main components identified(1).

2. Fungicidal and anti-aflatoxigenic effects

In the study to develop a natural fungicide against aflatoxigenic fungi, to protect stored rice, using the essential oil of lemongrass. showed that Lemongrass oil could be used to manage aflatoxin formation and fungal growth of A. flavus in stored rice(2).

3. Cytogenotoxicity

In the study to investigate the cytotoxic and genotoxic effects of aqueous extracts from C. citratus leaves on Lactuca sativa (lettuce) root tip meristem cell, found that the highest concentration of aqueous extracts reduced the mitotic index, the seed germination and the root development of lettuce. The extracts have also induced chromosome aberrations and cellular death in the roots cells of L. sativa(3).

4. Anticonvulsant activities

In the study to compare the effects of both EOs on three models of convulsions (pentylenetetrazol, pilocarpine, and strychnine) and on the barbiturate-induced sleeping time on male Swiss mice, showed that both EOs were more active on the pentylenetetrazol-induced convulsion model, and C. citratus was even more efficient in increasing latency to the first convulsion and latency to death. Both parameters were potentiated in the presence of a lower dose of diazepam (reference drug) when associated to a lower dose of each EO (25 mg kg(-1)). Besides, their anticonvulsant effects were blocked by flumazenil, a known benzodiazepine antagonist. This effect was somewhat lower on the pilocarpine-induced convulsion, and better effects were seen only with the EOs’ higher doses (200 mg kg(-1)). A similar result was observed on the strychnine-induced convulsion model. Both EOs potentiated the barbiturate-induced sleeping time. However, C. citratus was more efficient. Interestingly, both EOs completely blocked the MPO release from human neutrophils and showed no cytotoxic effect on the LDH release from human neutrophils(4).

5. Etc.

Side Effects

1. Do not use the herb in case of Yin deficiency with heat

2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.

3. Etc.